The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2019

Filed:

Oct. 02, 2017
Applicant:

National Health Research Institutes, Miaoli County, TW;

Inventors:

Tsung-Hsien Chuang, Miaoli County, TW;

Da-Wei Yeh, Miaoli County, TW;

Chao-Yang Lai, Miaoli County, TW;

Yi-Ling Liu, Miaoli County, TW;

Chih-Hao Lu, Miaoli County, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 38/19 (2006.01); A61K 39/12 (2006.01); A61K 39/39 (2006.01); A61K 45/06 (2006.01); C12N 15/117 (2010.01);
U.S. Cl.
CPC ...
C12N 15/117 (2013.01); A61K 39/39 (2013.01); A61K 2039/55561 (2013.01); C12N 2310/17 (2013.01);
Abstract

A CpG-oligodeoxynucleotide (CpG-ODN) for inducing a TLR9 activated immune response, a TLR21 activated immune response or a combination thereof in a host is provided. The CpG-ODN includes one or more copies of the sequences of GTCGTT, one or more copies of the sequences of GTT and one or more copies of the sequences of TTTT, wherein at least one copy of the sequence of GTCGTT is encoded between the sequence of GTT and the sequence of TTTT. Further, an immunogenic composition including the CpG-ODN and a method of inducing immune response by the same are also provided.


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