Location History:
- Cary, NC (US) (2010)
- Irvine, CA (US) (2010)
Company Filing History:
Years Active: 2010
Title: Tsu-shun Lee: Innovator in Polysaccharide Purification
Introduction
Tsu-shun Lee is a notable inventor based in Cary, NC (US). He has made significant contributions to the field of polysaccharide purification, holding 2 patents that showcase his innovative methods.
Latest Patents
His latest patents include a process for reducing the protein content while preserving the capsular polysaccharide content in a complex cellularlysate broth prior to purification. This method utilizes pH reduction after cellular lysis, resulting in a purified polysaccharide that consistently meets protein specifications and achieves higher recovery yields during the purification process. Another patent provides improved methods for the reduction or removal of protein impurities from a complex cellularlysate or centrate comprising serotype 3 polysaccharides. This involves post-lysis heating or pH adjustment, where the lysate is heated to at least 60°C for a sufficient time to denature proteins, causing their aggregation and precipitation.
Career Highlights
Tsu-shun Lee is currently employed at Wyeth, where he continues to develop innovative solutions in his field. His work has significantly advanced the methods used in polysaccharide purification, contributing to the efficiency and effectiveness of the processes involved.
Collaborations
He has collaborated with notable coworkers such as Brian Bahler and Jason Arnold Lotvin, further enhancing the innovative environment in which he works.
Conclusion
Tsu-shun Lee's contributions to polysaccharide purification through his patents reflect his dedication to innovation in the field. His work not only advances scientific understanding but also improves practical applications in the industry.