Houston, TX, United States of America

Tse-wen Chang


Average Co-Inventor Count = 1.6

ph-index = 10

Forward Citations = 300(Granted Patents)


Company Filing History:


Years Active: 1992-1999

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11 patents (USPTO):Explore Patents

Title: Innovations of Tse-wen Chang in HIV-1 Research

Introduction

Tse-wen Chang is a notable inventor based in Houston, TX (US), recognized for his significant contributions to the field of biomedical research, particularly in the development of therapies targeting HIV-1. With a total of 11 patents to his name, Chang's work has the potential to impact the treatment and prevention of AIDS and related conditions.

Latest Patents

Chang's latest patents include groundbreaking innovations such as chimeric monoclonal antibodies that neutralize HIV-1 infection. These antibodies specifically bind to the gp120 protein on the envelope of HIV-1, effectively neutralizing the virus. They inhibit the rate of infection of T cells and prevent syncytium formation. Importantly, these antibodies are group-specific, allowing them to neutralize various strains and isolates of HIV-1. Their applications extend to the treatment and prevention of AIDS and AIDS-related complex (ARC). Another significant patent involves immunoconjugates that also neutralize HIV-1 infection, utilizing the same mechanism of action to target and inhibit HIV-1 infected T cells.

Career Highlights

Throughout his career, Tse-wen Chang has worked with prominent companies in the biotechnology sector, including Tanox Biosystems, Inc. and Tanox, Inc. His innovative research has positioned him as a key figure in the fight against HIV-1, contributing to advancements that could lead to more effective treatments.

Collaborations

Chang has collaborated with notable colleagues in his field, including Nancy T. Chang and Bill Nai-Chau Sun. These partnerships have fostered a collaborative environment that enhances the development of innovative solutions in HIV research.

Conclusion

Tse-wen Chang's contributions to HIV-1 research through his patents and collaborations highlight his commitment to advancing medical science. His work not only addresses critical health challenges but also paves the way for future innovations in the treatment and prevention of viral infections.

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