This inventor holds 1 USPTO granted patent. Top assignee: Boyce Thompson Institute for Plant Research. Active years: 2002.
Company Filing History:
Years Active: 2002
Title: Tsafrir S Mor: Innovator in Plant Genetic Engineering
Introduction
Tsafrir S Mor is a prominent inventor based in Ithaca, NY (US). He has made significant contributions to the field of plant genetic engineering, particularly in the development of systems for gene expression in plants. His innovative work aims to enhance the production of foreign proteins in agricultural settings.
Latest Patents
Tsafrir S Mor holds a patent for "Gemini virus vectors for gene expression in plants." This patent describes a gene amplification system that utilizes plant viral genetic elements to dramatically increase foreign protein production in plants. The system offers a safer and more economical method for producing vaccines and antibodies in recombinant plants, which can be cultivated using standard agricultural practices. The high-level expression system leverages the replicative process of a plant mastrevirus, specifically the bean yellow dwarf virus (BeYDV). This expression system is designed to be inducible, minimizing any potential interference with plant growth and development. Developmental cues, such as fruit ripening, are utilized to trigger the expression of foreign proteins through a tissue-specific promoter. The system allows for a single, stably integrated expression cassette for foreign proteins to be replicated extrachromosomally in ripening fruit, resulting in hundreds of transcriptionally competent copies. Preferred plant hosts for this system include tomato as a model and soybean for the large-scale production of proteins at high total protein levels.
Career Highlights
Tsafrir S Mor is affiliated with the Boyce Thompson Institute for Plant Research, where he continues to advance research in plant biotechnology. His work has garnered attention for its potential applications in agriculture and medicine.
Collaborations
He has collaborated with notable colleagues, including Kathleen L Hefferon and Kenneth E Palmer, contributing to the advancement of plant genetic research.
Conclusion
Tsafrir S Mor's innovative work in plant genetic engineering exemplifies the potential of biotechnology to enhance agricultural practices and improve protein production. His contributions are paving the way for safer and more efficient methods in the field.