Tristan Bepler

Title: Innovations of Inventor Tristan Bepler

Introduction

Tristan Bepler is an accomplished inventor based in Hillsborough, NC (US). He has made significant contributions to the field of cryo-electron microscopy and protein database search technologies. With a total of two patents to his name, Bepler's work is at the forefront of scientific innovation.

Latest Patents

Bepler's latest patents include "Automating cryo-electron microscopy data collection" and "Protein database search using learned representations." The first patent describes a method for automated control of a microscope in cryogenic electron microscopy (cryo-EM). This method allows for the collection of high-magnification micrographs of particles suspended in vitreous ice. The process leverages a pipeline that evaluates collection locations based on quality scores derived from pretrained models and machine learning-based active learning. The second patent focuses on an efficient method for searching protein sequence databases. It transforms protein sequences into vector representations, enabling rapid retrieval of proteins based on their homology to a query sequence.

Career Highlights

Throughout his career, Bepler has worked with notable organizations such as the New York Structural Biology Center and Ne47 Bio, Inc. His expertise in cryo-electron microscopy and protein analysis has positioned him as a key figure in his field.

Collaborations

Bepler has collaborated with esteemed colleagues, including Paul T. Kim and Bonnie Berger Leighton. These partnerships have further enhanced his research and contributions to scientific advancements.

Conclusion

Tristan Bepler's innovative work in cryo-electron microscopy and protein database search technologies showcases his dedication to advancing scientific research. His patents reflect a commitment to improving methodologies in these critical areas.