Location History:
- Seattle, WA (US) (2021 - 2023)
- Bothell, WA (US) (2024)
Company Filing History:
Years Active: 2021-2024
Title: Innovations of Travis Biechele
Introduction
Travis Biechele is an accomplished inventor based in Seattle, WA, known for his significant contributions to the field of biotechnology. With a total of four patents to his name, Biechele has made strides in developing innovative solutions that enhance therapeutic applications.
Latest Patents
Among his latest patents is the invention titled "Cysteine mutated antibodies for conjugation." This invention provides modified heavy chain constant regions that include a cysteine at position 295 by EU numbering, and optionally at position 239. These cysteine residues create sites for conjugation to a drug or label, allowing a stoichiometry of one molecule of antibody to four of drug or label. The selection of the cysteine at position 295, with or without cysteine at position 239, is advantageous due to ease of expression, stability, and reduced cytotoxicity. Another notable patent is "Glypican 3 antibodies and conjugates thereof," which provides murine, chimeric, and humanized antibodies that specifically bind to GPC3 and their conjugates.
Career Highlights
Travis Biechele has established a successful career at Seagen Inc., where he continues to innovate in the field of antibody development. His work focuses on creating targeted therapies that can significantly improve patient outcomes.
Collaborations
Biechele collaborates with talented individuals such as William Arthur and Rory Rohm, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Travis Biechele's work exemplifies the spirit of innovation in biotechnology, with his patents paving the way for advancements in therapeutic applications. His contributions are vital to the ongoing development of effective treatments in the medical field.