Location History:
- Ohtsu, JP (1996)
- Ohtu, JP (1998)
- Otu, JP (1999)
Company Filing History:
Years Active: 1996-1999
Title: Toshiya Aono: Innovator in Nucleic Acid Amplification
Introduction
Toshiya Aono is a prominent inventor based in Ohtsu, Japan. He has made significant contributions to the field of nucleic acid amplification, holding a total of 3 patents. His work focuses on improving the sensitivity and efficiency of nucleic acid detection methods.
Latest Patents
Aono's latest patents include innovative methods for nucleic acid amplification utilizing thermostable ribonuclease H. These methods allow for the preparation of single-stranded RNA (-) from RNA (+) as a target nucleic acid. The copy number of the single-stranded RNA (-) is increased through the use of thermostable ribonuclease H in combination with various non-thermostable polymerases. This advancement enhances the number of amplification cycles and improves detection sensitivity compared to conventional methods. Additionally, he has developed oligonucleotides, methods, and kits for amplifying and detecting cytomegalovirus (CMV) nucleic acids. These innovations enable rapid and specific detection of CMV with high sensitivity.
Career Highlights
Aono is associated with Toyo Boseki Kabushiki Kaisha, where he continues to advance his research and development efforts. His work has garnered attention for its practical applications in medical diagnostics and research.
Collaborations
Some of his notable coworkers include Motohiro Kondo and Katsuya Daimon, who have collaborated with him on various projects related to nucleic acid amplification.
Conclusion
Toshiya Aono's contributions to nucleic acid amplification represent a significant advancement in the field, enhancing detection methods and improving sensitivity. His innovative patents continue to influence research and diagnostics in molecular biology.