This inventor holds 1 USPTO granted patent. Top assignee: Toshin Chemical Co., Ltd.. Active years: 1986.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1986
Title: Innovations of Toshio Itoh in Medicinal Chemistry
Introduction
Toshio Itoh is a notable inventor based in Urawa, Japan. He has made significant contributions to the field of medicinal chemistry, particularly in the development of novel compounds for treating heart disorders. His innovative approach has led to the creation of a unique method for synthesizing important medicinal compounds.
Latest Patents
Toshio Itoh holds a patent for a method for the preparation of isosorbide-5-nitrate. This method presents a novel and efficient way to synthesize isosorbide-5-nitrate, which is recognized for its potential in treating various heart-related diseases. The process involves the direct nitration of isosorbide using concentrated nitric acid in a specific reaction medium that includes aromatic hydrocarbon solvents, such as benzene, along with conventional acetic acid and acetic anhydride. After neutralizing the reaction mixture and removing the dinitrate byproduct, the mixture is treated with an aqueous sodium hydroxide solution, resulting in the precipitation of a sodium salt of isosorbide-5-nitrate in the form of a hydrate. This hydrate is then decomposed with an acid to yield isosorbide-5-nitrate in high yield.
Career Highlights
Toshio Itoh is associated with Toshin Chemical Co., Ltd., where he has been instrumental in advancing research and development in medicinal chemistry. His work has not only contributed to the scientific community but has also paved the way for new therapeutic options in the medical field.
Collaborations
Toshio Itoh has collaborated with notable colleagues, including Susumu Ishiguro and Fumitake Shimada. Their combined expertise has fostered an environment of innovation and discovery within their research endeavors.
Conclusion
Toshio Itoh's contributions to medicinal chemistry, particularly through his patent for isosorbide-5-nitrate, highlight his role as a significant inventor in the field. His innovative methods and collaborations continue to influence the development of new treatments for heart disorders.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile