Location History:
- Kita-ku, JP (2001)
- Kobe, JP (2003 - 2007)
- Rockville, MD (US) (1999 - 2008)
Company Filing History:
4 out of 3,539 
1 out of 1,217 
Years Active: 1999-2008
Title: The Innovative Contributions of Toshimitsu Matsui
Introduction
Toshimitsu Matsui, a distinguished inventor based in Kobe, Japan, holds five patents that reflect his significant contributions to the field of biotechnology. His work focuses on the human platelet-derived growth factor (PDGF) receptor, which plays a crucial role in various biological processes. Matsui’s research and inventions have advanced the understanding of protein interactions and potential therapeutic applications.
Latest Patents
Matsui's latest patents include groundbreaking work on compositions related to the alpha platelet-derived growth factor receptor nucleic acid and protein. One notable patent describes a DNA sequence encoding a human type α platelet-derived growth factor receptor protein that preferentially binds to the AA homodimer and AB heterodimer forms of platelet-derived growth factor, with high-affinity binding to the BB homodimer. This patent details methods for the recombinant production of substantially pure human α platelet-derived growth factor receptor protein. Additionally, he has developed methods for identifying alpha PDGFR agonists and antagonists, which utilize recombinant DNA technology to produce unique human PDGF receptor proteins. These advancements enable biochemical studies and the production of antibodies for further research.
Career Highlights
Throughout his career, Matsui has been associated with prominent institutions such as the United States Department of Health and Human Services, where he has contributed to numerous significant research initiatives. His extensive work with PDGF receptors has positioned him as a key figure in the advancement of therapeutic approaches for various medical conditions.
Collaborations
Matsui has collaborated with notable researchers, including Stuart A. Aaronson and Jacalyn H. Pierce. These collaborations have been instrumental in the development of his innovations, further enhancing the quality and impact of his research in the biotechnology sector.
Conclusion
Toshimitsu Matsui's innovative work and patents in the field of biotechnology exemplify the importance of research in developing new medical therapies. His contributions to understanding platelet-derived growth factor receptors have the potential to influence treatment strategies for various health conditions, marking him as a prominent inventor in his field.