Location History:
- Hachioji, JP (2006)
- Tokyo, JP (2005 - 2014)
Company Filing History:
3 out of 62 
2 out of 2 
1 out of 856 
Years Active: 2005-2014
Title: Toshiaki Isobe: Innovator in Ribonucleic Acid Identification
Introduction
Toshiaki Isobe is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the field of molecular biology, particularly in the identification of ribonucleic acids (RNA). With a total of 5 patents, his work has advanced the understanding and application of RNA identification techniques.
Latest Patents
Isobe's latest patents include a ribonucleic acid identification apparatus, method, program, and system. These innovations disclose an apparatus that enhances the identification of RNA by obtaining not only the molecular weights of digestion products but also nucleic acid residue sequence data. This dual approach significantly improves the reliability of identifying individual digestion products. The method involves searching a nucleic acid sequence database using a fragment mass set derived from tandem mass spectrometry on digested oligonucleotides. The process scores candidate sequences and identifies those that exceed a certain threshold, facilitating accurate mapping on genomic sequences.
Another notable patent is the nano-electrospray ionization technique and device. This technique involves introducing a separation solvent containing a sample to a column-integrated needle filled with resin for liquid chromatography. The separated sample components are then sprayed toward a mass spectrometer, enhancing the efficiency of sample analysis.
Career Highlights
Throughout his career, Toshiaki Isobe has worked with esteemed institutions such as Tokyo Metropolitan University and Nano Solution, Inc. His research has been pivotal in advancing the methodologies used in RNA identification, making him a respected figure in the scientific community.
Collaborations
Isobe has collaborated with notable colleagues, including Yoshio Yamauchi and Tohru Natsume. These partnerships have contributed to the development of innovative solutions in the field of molecular biology.
Conclusion
Toshiaki Isobe's contributions to RNA identification through his patents and collaborations have significantly impacted the field of molecular biology. His innovative approaches continue to pave the way for advancements in genetic research and applications.