Toru Sawai

Title: **Toru Sawai: Innovations in Feeding and Anxiety Therapeutics**

Introduction

Toru Sawai, an accomplished inventor based in Tsukuba, Japan, has made significant contributions to the fields of pharmacology and nutrition. With two patents to his name, his work has focused on developing innovative methods to influence feeding behavior and to screen for potential anxiolytic drugs.

Latest Patents

One of Sawai’s latest inventions involves the "Methods of affecting feeding and weight in mammals by administration of relaxin-3." This research reveals that relaxin-3 demonstrates feeding-stimulating activity, as well as effects on body weight and fat weight in rats. The invention encompasses a polypeptide that stimulates feeding and promotes weight gain. Additionally, it includes a therapeutic agent that utilizes this polypeptide, a method for screening compounds that activate or suppress its receptor, and a kit for conducting such screenings. The invention also considers agents that inhibit the expression of the polypeptide, making it potentially useful for developing treatments for obesity and diabetes.

Another groundbreaking patent from Sawai pertains to the "Method of screening for antianxiety drugs." This invention identifies an anxiolytic drug that comprises an orexin receptor antagonist. The method introduces the use of orexin-A as a step in the screening process for compounds that exhibit anxiolytic action.

Career Highlights

Toru Sawai is currently affiliated with Eisai R&D Management Co., Ltd., where his research focuses on the development of pharmacological agents that address critical health issues. His expertise and innovative approaches have positioned him as a valuable asset in the pharmaceutical field, particularly in relation to body weight management and anxiety disorders.

Collaborations

During his career, Sawai has collaborated with notable colleagues including Takayuki Hida and Tomoko Sekiya. These partnerships have likely contributed to the success of his patents and the innovative solutions they provide within their respective fields.

Conclusion

Toru Sawai's inventive contributions represent a significant advancement in the understanding and treatment of feeding behaviors and anxiety disorders. His ongoing research and patents not only enhance the scientific community’s knowledge but also offer promising therapeutic options for conditions that affect countless individuals worldwide. As innovations continue to emerge from his work, they may pave the way for new strategies in both nutritional and mental health management.