Torben Ravn Rasmussen

Title: Torben Ravn Rasmussen: Innovator in Molecular Encoding

Introduction

Torben Ravn Rasmussen is a notable inventor based in Ballerup, Denmark. He has made significant contributions to the field of molecular encoding, with a focus on methods for obtaining structural information about encoded molecules and selecting compounds that bind to specific targets. His innovative work has led to the filing of three patents.

Latest Patents

Rasmussen's latest patents include a method for obtaining structural information concerning an encoded molecule. This method involves producing an encoded molecule through a reaction of various chemical entities, which can be connected to an identifier oligonucleotide. This oligonucleotide contains codons that provide information about the identity of the chemical entities involved in the formation of the encoded molecule. In one embodiment, primers are designed to be complementary to the codons on the identifier oligonucleotide. The presence, absence, or relative abundance of a codon is evaluated by mixing a primer with the identifier oligonucleotide in the presence of a polymerase and substrate (deoxy)ribonucleotide triphosphates, measuring the extension reaction.

Another aspect of his invention relates to a method for selecting compounds that bind to a target. This method involves mixing a target associated with an oligonucleotide with a library of complexes, each comprising a display molecule and an oligonucleotide identifying that display molecule. Due to increased proximity, the target oligonucleotide is coupled to the identifier oligonucleotide of complexes that have a display molecule with affinity towards the target. The coupled nucleotides are then analyzed to deduce the identity of the display molecule.

Career Highlights

Torben Ravn Rasmussen is currently associated with Nuevolution A/S, where he continues to advance his research and development in molecular encoding technologies. His work has been instrumental in enhancing the understanding of molecular interactions and the development of new compounds.

Collaborations

Rasmussen has collaborated with notable colleagues such as Thomas Thisted and Mikkel Dybro Lundorf, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

Torben Ravn Rasmussen is a distinguished inventor whose work in molecular encoding has led to significant advancements in the field. His innovative patents and collaborations reflect his commitment to pushing the boundaries of scientific research.