Tongjia Yin

Title: Innovations of Tongjia Yin in Nucleic Acid Sequencing

Introduction

Tongjia Yin is a notable inventor based in San Diego, California. He has made significant contributions to the field of nucleic acid sequencing, holding two patents that enhance the accuracy and efficiency of sequence determinations. His work is pivotal in advancing genetic research and diagnostics.

Latest Patents

Tongjia Yin's latest patents focus on algorithms for determining consensus sequences from multiple raw sequencing reads of a nucleic acid target. The invention provides methods that include an anchor segment of known sequence and an adjacent segment of unknown sequence. The anchor segment serves as a quality assessment tool for raw target sequencing reads. Those reads that meet or exceed a certain threshold are classified as accepted. The consensus sequence of the adjacent segment is derived from these accepted reads. Successive polling steps are employed to determine the consensus nucleobases in a nascent sequence of the adjacent segment. Additionally, raw target sequencing reads can be either removed or reintroduced into the accepted class based on their alignment with the most recently determined consensus nucleobase and/or the nascent sequence.

Career Highlights

Tongjia Yin is currently associated with Gen-Probe, Inc., where he continues to innovate in the field of genetic sequencing. His work has been instrumental in developing methods that improve the reliability of sequencing technologies.

Collaborations

Some of his notable coworkers include Jennifer Jill Bungo and Xianqun Wang, who collaborate with him on various projects related to nucleic acid sequencing.

Conclusion

Tongjia Yin's contributions to the field of nucleic acid sequencing through his innovative patents are significant. His work not only enhances the understanding of genetic material but also paves the way for advancements in medical diagnostics and research.