Company Filing History:
Years Active: 2000-2009
Title: Innovations by Inventor Tong Shangguan
Introduction
Tong Shangguan is a notable inventor based in Princeton, NJ (US). He has made significant contributions to the field of liposomal delivery systems, holding a total of 4 patents. His work focuses on encapsulating bioactive agents, which has important implications for drug delivery and biotechnology.
Latest Patents
One of his latest patents is titled "Encapsulation of bioactive complexes in liposomes." This invention provides a method to prepare liposome-encapsulated bioactive agents such as nucleic acids. It involves the complexation of the bioactive agents in reverse micelles prior to forming liposomes, as well as methods of using the liposomes formed and formulations to deliver nucleic acids to cells. Another significant patent is the "Modular targeted liposomal delivery system." This patent describes a liposome that includes a fusogenic liposome, a linking moiety, and a targeting moiety. The fusogenic liposome is a lipid bilayer encapsulating contents, while the linking moiety is electrostatically bound to the lipid bilayer. The targeting moiety is covalently bound to the linking moiety, enhancing the specificity of the delivery system.
Career Highlights
Throughout his career, Tong Shangguan has worked with prominent companies in the biotechnology sector. Notably, he has been associated with The Liposome Company, Inc. and Transave Limited. His work in these organizations has contributed to advancements in drug delivery technologies.
Collaborations
Tong has collaborated with esteemed colleagues such as Paul R. Meers and Andrew S. Janoff. These collaborations have further enriched his research and innovations in the field.
Conclusion
Tong Shangguan's contributions to liposomal delivery systems and his innovative patents highlight his role as a significant inventor in the biotechnology field. His work continues to influence advancements in drug delivery and bioactive agent encapsulation.
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