Tomonori Yaguchi

Title: Innovations of Tomonori Yaguchi

Introduction

Tomonori Yaguchi is a notable inventor based in Tokyo, Japan. He has made significant contributions to the field of medical technology, particularly in cancer treatment. His work focuses on developing innovative solutions to combat squamous cell carcinoma.

Latest Patents

Yaguchi holds a patent for an "Anti-glypican-1-immunizing antigen receptor." The purpose of this invention is to produce a chimeric antigen receptor (CAR) that is specific to glypican-1 (GPC-1). This CAR aims to treat squamous cell carcinoma using genetically modified cells capable of expressing the receptor. The invention includes a chimeric antigen receptor designed for the treatment and/or prevention of squamous cell carcinoma, which comprises an extracellular domain that binds to GPC-1, a transmembrane domain, and one or multiple intracellular domains. At least one of these intracellular domains contains a primary cytosolic signaling sequence or both a primary and a secondary cytosolic signaling sequence. Additionally, the invention encompasses genetically modified cells that can express the chimeric antigen receptor and a cell preparation containing these cells.

Career Highlights

Throughout his career, Yaguchi has worked with prestigious institutions, including Keio University and Kochi University. His research has focused on advancing medical technologies and improving treatment options for cancer patients.

Collaborations

Yaguchi has collaborated with notable colleagues, including Kenji Morii and Yutaka Kawakami. Their combined expertise has contributed to the development of innovative solutions in the medical field.

Conclusion

Tomonori Yaguchi's work exemplifies the impact of innovation in medical technology, particularly in the fight against cancer. His contributions through patents and collaborations highlight the importance of research and development in improving patient outcomes.