Tomohiro Hata

Title: Tomohiro Hata and a Cell Culture Method for Blood-Brain Barrier Models.

Introduction

Tomohiro Hata is an inventor associated with Yamaguchi University in Yamaguchi, Japan. His work includes a cell culture method and device designed to support the production of in vitro models of the blood-brain barrier (BBB).

Latest Patents

Hata is credited with 1 patent: “Cell Culture Method and Cell Culture Device Used with Cell Culture Method.” The invention describes a process for producing a three-layer BBB model containing vascular endothelial cells, pericytes, and astrocytes. The method cultures astrocytes on a porous membrane, then seeds pericytes while the cell culture insert is inverted, and subsequently cultures vascular endothelial cells embedded in a temperature-sensitive gel. The gel is then melted. This approach is intended to make mass production of the three-layer models more practical.

Career Highlights

Hata’s listed patent focuses on a cell culture technique and device for creating a complex in vitro model relevant to BBB research. The method’s sequential cell-seeding steps bring together three cell types associated with the barrier.

Collaborations

Susumu Fujikawa is identified as Hata’s coworker. The available information does not specify further details about their collaboration.

Conclusion

Tomohiro Hata’s patent presents a structured cell culture approach for producing three-layer BBB models, with the goal of enabling their mass production for research.