Company Filing History:
Years Active: 2021-2025
Title: The Innovations of Tomofumi Nakada
Introduction
Tomofumi Nakada is a prominent inventor based in Kobe, Japan. He has made significant contributions to the field of antibody engineering, holding a total of 3 patents. His work focuses on improving the affinity and stability of antibodies, which has important implications for therapeutic applications.
Latest Patents
One of Nakada's latest patents is a method for improving the affinity of an antibody for an antigen. This method involves changing at least three amino acid residues in the framework region 3 (FR3) of the antibody to arginine or lysine residues. This modification enhances the antibody's affinity for the antigen compared to its original form. Another notable patent is a method for improving the thermal stability of antibodies. This method includes modifying specific amino acid residues in the heavy chain of the antibody to cysteine residues, which helps in producing a more stable modified antibody.
Career Highlights
Tomofumi Nakada is currently employed at Sysmex Corporation, where he continues to innovate in the field of antibody research. His work has been instrumental in advancing the understanding of antibody interactions and stability, contributing to the development of more effective therapeutic agents.
Collaborations
He has collaborated with notable colleagues such as Nobuyuki Ide and Yuriko Egashira, further enhancing the research output and innovation at Sysmex Corporation.
Conclusion
Tomofumi Nakada's contributions to antibody engineering through his innovative patents demonstrate his commitment to advancing medical science. His work not only improves the efficacy of therapeutic antibodies but also sets a foundation for future research in this critical area.