Todd M Greco

Title: Todd M Greco: Innovator in Cellular Biology

Introduction

Todd M Greco is a notable inventor based in Langhorne, PA (US). He has made significant contributions to the field of cellular biology, particularly in understanding the mechanisms of various cellular processes. With a total of 4 patents to his name, Greco's work has implications for both scientific research and potential therapeutic applications.

Latest Patents

One of his latest patents is focused on the lipoamidase activity of Sirtuin 4 (SIRT4) and its uses. This patent provides a method for assaying pyruvate dehydrogenase complex (PDHC) activity in mammalian cells expressing human SIRT4. The method involves measuring the level of a dihydrolipoyllysine acetyltransferase (DLAT) lipoamide peptide in the cell. Additionally, this application demonstrates that SIRT4 acts as a cellular lipoamidase that negatively regulates PDHC activity through the hydrolysis of its lipoamide cofactors. Another significant patent involves a method to increase the infectivity of virus particles, specifically enhancing the infectivity of HCMV virus particles.

Career Highlights

Todd M Greco is affiliated with Princeton University, where he continues to advance research in cellular biology. His work has garnered attention for its innovative approaches to understanding complex biological systems.

Collaborations

Greco has collaborated with esteemed colleagues such as Thomas E Shenk and Ileana M Cristea, contributing to a rich environment of scientific inquiry and discovery.

Conclusion

Todd M Greco's contributions to cellular biology through his patents and research at Princeton University highlight his role as an influential inventor in the field. His innovative methods and collaborative efforts continue to push the boundaries of scientific understanding.