This inventor holds 1 USPTO granted patent and 2 published patent applications. Top assignee: Laboratory Corporation of America Holdings. Active years: 2025.
Company Filing History:
Years Active: 2025
Title: Toby Manders: Innovator in Population Frequency Modeling
Introduction
Toby Manders is a notable inventor based in San Francisco, CA. He has made significant contributions to the field of genetics through his innovative patent. His work focuses on improving the understanding of variant pathogenicity estimation, which is crucial for genetic research and medical applications.
Latest Patents
Toby Manders holds a patent titled "Population frequency modeling for quantitative variant pathogenicity estimation." This patent involves the application of a logistic regression model to a set of population data for various genes. The model utilizes features that quantify the predictive value of allele frequency within a gene. By evaluating the output of the logistic regression model against expected variant classifications, the model is refined to produce accurate variant pathogenicity estimates. This innovative approach enhances the ability to classify genetic variants effectively.
Career Highlights
Toby Manders is currently employed at Laboratory Corporation of America Holdings, a leading company in the field of laboratory testing and diagnostics. His work at this organization allows him to apply his expertise in genetics and contribute to advancements in medical research.
Collaborations
Toby collaborates with talented professionals in his field, including Alexandre Colavin and Keith Nykamp. These collaborations foster an environment of innovation and shared knowledge, further enhancing the impact of their work.
Conclusion
Toby Manders is a distinguished inventor whose work in population frequency modeling has the potential to significantly advance the field of genetics. His contributions are vital for improving variant pathogenicity estimation, which can lead to better understanding and treatment of genetic disorders.