Ting-Gung Chang

Title: Innovations of Ting-Gung Chang in Peptide-Spacer-Lipid Conjugates

Introduction

Ting-Gung Chang is a notable inventor based in Taipei, Taiwan. He has made significant contributions to the field of biotechnology, particularly in the synthesis of peptide-spacer-lipid conjugates. His innovative work has implications for targeted drug delivery systems.

Latest Patents

Ting-Gung Chang holds a patent for a solid phase method for synthesizing peptide-spacer-lipid conjugates. This patent, titled "Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same," outlines a convenient solid phase synthesis method for preparing these conjugates. The method allows for various linkage groups, such as amide groups, to conjugate peptide, spacer, and lipid, with the spacer potentially comprising PEG. The advantages of this synthesis method include simplified procedures, automation potential, easier purification at each reaction step, and minimal product loss during synthesis. This method is suitable for preparing a wide range of peptide-spacer-lipid conjugates, which can be incorporated into liposomes for targeted drug delivery to specific cells.

Career Highlights

Ting-Gung Chang is associated with the Development Center for Biotechnology, where he continues to advance research in biotechnology and drug delivery systems. His work has garnered attention for its practical applications in medical science.

Collaborations

Ting-Gung Chang has collaborated with notable colleagues, including Shih-Kwang Wu and Chin-Lu Tseng, contributing to the advancement of their shared research goals.

Conclusion

Ting-Gung Chang's innovative approach to synthesizing peptide-spacer-lipid conjugates represents a significant advancement in biotechnology. His contributions are paving the way for more effective drug delivery systems, showcasing the importance of innovation in the medical field.