Location History:
- Jamaica Plain, MA (US) (2004 - 2005)
- Needham, MA (US) (2012)
Company Filing History:
Years Active: 2004-2012
Title: Innovations and Contributions of Timothy S. Gardner
Introduction
Timothy S. Gardner is a notable inventor based in Needham, MA, with a significant contribution to the field of biotechnology. He holds four patents that showcase his innovative approaches to understanding and manipulating gene expression. His work has implications for various applications in genetic research and synthetic biology.
Latest Patents
One of his latest patents is a method to determine transcriptional regulation pathways in organisms. This invention relates to computer-implemented methods and systems for identifying regulatory relationships between expressed regulating polypeptides and their targets. It provides a new method for identifying regulatory dependencies between biochemical species in a cell. Specifically, it includes methods for identifying regulatory interactions between transcription factors and gene targets, as well as genome-scale methods for predicting regulatory interactions.
Another significant patent is the bistable genetic toggle switch. This invention offers methods and compositions for regulating gene expression in a cell. It includes recombinant genetic toggle switches that consist of two operons, where the expression of one regulatory gene inhibits the expression of the other. This toggle switch allows for the reversible switching of gene expression between stable 'on' and 'off' states, providing a powerful tool for genetic manipulation.
Career Highlights
Timothy S. Gardner has worked with prominent organizations such as Cellicon Technologies, Inc. and Boston University. His experience in these institutions has contributed to his development as an inventor and researcher in the field of biotechnology.
Collaborations
He has collaborated with notable individuals in his field, including James Joseph Collins and Boris Hayete. These collaborations have likely enriched his research and innovation efforts.
Conclusion
Timothy S. Gardner's contributions to biotechnology through his patents and collaborations highlight his role as a significant inventor in the field. His innovative methods for gene regulation and expression continue to influence research and applications in genetic engineering.