Company Filing History:
Years Active: 2022
Title: Innovations in Ovarian Cancer Research by Tilly Jenkins Vogel
Introduction
Tilly Jenkins Vogel is an accomplished inventor based in Los Angeles, CA. She has made significant contributions to the field of ovarian cancer research through her innovative work. Her research focuses on the development of in vitro models that can enhance the understanding of high-grade serous ovarian cancer (HGSC).
Latest Patents
Tilly holds a patent for "Methods and compositions for production of fallopian tube epithelium." This patent addresses the challenges in studying the fallopian tube epithelium (FTE), which is recognized as a potential origin site for HGSC. The absence of relevant in vitro human models has limited research in this area. Tilly's work utilizes induced pluripotent stem cells (iPSCs) to create a novel three-dimensional (3D) human FTE organoid model. This model closely mimics the architecture of human fallopian tissues, allowing for a better understanding of FTE transformation and the initiation of HGSC.
Career Highlights
Tilly is affiliated with Cedars-Sinai Medical Center, where she continues her groundbreaking research. Her innovative approach has led to the establishment of a powerful human-derived FTE organoid model. This model can be utilized to study the earliest stages of HGSC development and to identify novel biomarkers for early fallopian tube epithelial cell transformation.
Collaborations
Tilly collaborates with esteemed colleagues, including Clive N Svendsen and Beth Y Karlan. Their combined expertise enhances the research efforts in understanding ovarian cancer and developing effective models for study.
Conclusion
Tilly Jenkins Vogel's contributions to ovarian cancer research through her innovative patent and collaborative efforts are paving the way for advancements in understanding this disease. Her work holds promise for identifying new biomarkers and improving therapeutic strategies for high-grade serous ovarian cancer.