Tian Qin

Title: Innovations of Inventor Tian Qin

Introduction

Tian Qin is a notable inventor based in Dallas, TX (US). He has made significant contributions to the field of chemistry, particularly in the development of methods for synthesizing boronic acid compounds. With a total of 2 patents, his work has implications for medicinal chemistry and drug development.

Latest Patents

Tian Qin's latest patents focus on Cu- and Ni-catalyzed decarboxylative borylation reactions. These inventions are directed towards methods of converting a carboxylic acid group in a compound into a corresponding boronic ester. This process involves treatment with bis(pinacolato)diboron-alkyllithium complex in the presence of a ligand, a Ni(II) salt or a copper salt, and an Mg(II) salt. The resulting pinacolato boronate ester can be cleaved to yield a boronic acid. His inventions also encompass methods for preparing various compounds of medical value that contain boronic acid groups. Notable compounds include atorvastatin boronic acid analogs, vancomycin aglycone boronic acid analogs, and boronic acid-containing elastase inhibitors such as mCBK319, mCBK320, mCBK323, and RPX-7009.

Career Highlights

Tian Qin is affiliated with The Scripps Research Institute, where he continues to advance his research in synthetic chemistry. His innovative approaches have garnered attention in the scientific community, contributing to the development of new therapeutic agents.

Collaborations

Some of his notable coworkers include Phil Baran and Chao Li, who are also recognized for their contributions to the field of chemistry.

Conclusion

Tian Qin's work exemplifies the intersection of innovation and medicinal chemistry, showcasing the potential of boronic acid compounds in drug development. His contributions continue to influence the field and pave the way for future advancements.