Durham, NC, United States of America

Thomas Spector

USPTO Granted Patents = 14 


 

Average Co-Inventor Count = 2.8

ph-index = 3

Forward Citations = 33(Granted Patents)


Company Filing History:


Years Active: 1988-2014

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14 patents (USPTO):Explore Patents

Title: Thomas Spector: Innovations in Neurotoxicity Prevention

Introduction

Thomas Spector is a prolific inventor based in Durham, NC, who has made significant contributions to medical science, particularly in the realm of neurotoxicity. With a total of 14 patents to his name, Spector's work has focused on enhancing the effectiveness of cancer treatments while minimizing the associated risks.

Latest Patents

Among his latest inventions are methods designed to prevent or reduce neurotoxicity associated with administering dihydropyrimidine dehydrogenase (DPD) inhibitors in combination with 5-fluorouracil (5-FU) and 5-FU prodrugs. Spector has developed innovative techniques for administering these compounds, detailed in the following patents:

1. **Methods for preventing or reducing neurotoxicity associated with administering DPD inhibitors in combination with 5-FU and 5-FU prodrugs** - This method involves the sequential administration of a DPD inhibitor followed by 5-FU or its prodrug, ensuring that the level of 5-FU in the patient substantially exceeds that of the DPD inhibitor.

2. **Methods for administering DPD inhibitors in combination with 5-FU and 5-FU prodrugs** - Similar to his previous work, this patent outlines improved dosing protocols for administering DPD inhibitors along with 5-FU to enhance therapeutic effects while mitigating potentially harmful side effects.

Career Highlights

Spector's career has included vital roles at notable pharmaceutical companies such as Glaxo Wellcome Inc. and Burroughs Wellcome Company. His expertise in pharmacology and drug delivery systems has enabled him to make advancements that are imperative for enhancing patient care and treatment methodologies.

Collaborations

Throughout his career, Thomas Spector has collaborated with esteemed colleagues, including Saad George Rahim and David J.T. Porter. These collaborations have fostered an environment of innovation and have contributed to Spector's success as an inventor in the pharmaceutical field.

Conclusion

Thomas Spector continues to be a key figure in the development of novel methods aimed at improving cancer therapies. His 14 patents underscore his commitment to innovation and improvement in patient outcomes. As research progresses, Spector's inventions may lead to safer, more effective treatments for those battling cancer.

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