Manassas, VA, United States of America

Thomas R Groel


Average Co-Inventor Count = 4.4

ph-index = 4

Forward Citations = 118(Granted Patents)


Company Filing History:


Years Active: 1997-2002

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4 patents (USPTO):Explore Patents

Title: Innovations by Thomas R. Groel in Erythrocyte Stabilization

Introduction

Thomas R. Groel is an accomplished inventor based in Manassas, Virginia, with a focus on advancements in the field of erythrocyte stabilization. He holds a total of four patents that contribute significantly to the medical and biological sciences. His work primarily revolves around methods for storing and preserving erythrocytes, which are crucial for transfusion medicine.

Latest Patents

One of Groel's latest patents involves a method for storing tissues and cells, particularly erythrocytes. This method includes stabilizing the cells with a reversible stabilizing agent, loading them with a cryoprotectant, and storing them in various states such as liquid, frozen, or dry. A key aspect of this invention is the ability to reverse the stabilization reaction prior to use. The erythrocytes are pre-treated with carbon monoxide to complex the hemoglobin, which is anticipated to enhance their functionality upon reoxygenation. Additionally, Groel's invention includes a population of reversibly cross-linked erythrocytes that maintain their deformability and extend post-transfusion survival.

Career Highlights

Groel's career is marked by his innovative contributions to the field of erythrocyte research. His work has implications for improving the storage and viability of blood products, which is essential for effective transfusion practices. He is currently associated with the USA as represented by the Secretary of the Navy, where he continues to develop his groundbreaking methods.

Collaborations

Throughout his career, Groel has collaborated with notable colleagues such as Barry J. Spargo and Alan S. Rudolph. These collaborations have further enriched his research and contributed to the advancements in erythrocyte stabilization techniques.

Conclusion

Thomas R. Groel's innovative work in the field of erythrocyte stabilization has the potential to revolutionize blood storage and transfusion practices. His patents reflect a commitment to enhancing the safety and efficacy of medical treatments involving blood products.

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