Thomas R Flanagan

Title: **Innovations by Inventor Thomas R. Flanagan**

Introduction

Thomas R. Flanagan, an innovative inventor based in Barrington, Rhode Island, has made significant contributions to the field of biocompatible technologies. With a total of two patents under his name, Flanagan's work is centered around the development of advanced biological solutions for cell implantation and support.

Latest Patents

One of Flanagan's notable inventions is the creation of inner-supported, biocompatible cell capsules. This innovative capsule is designed to contain cells for implantation, featuring an inner support structure that enhances its tensile strength. The capsule is generally made from a tubular semipermeable membrane, such as a hollow fiber membrane, which is sealed at both ends. Within this capsule, cells can be suspended in a liquid medium or immobilized within a hydrogel or extracellular matrix material, allowing for the delivery of biologically active molecules across the membrane.

The inner support can be intricately designed with features like flutes or roughened surfaces, and may be coated with substances to improve cell adhesion and viability. Additionally, the design includes dual channels for efficient cell injection and gas escape, ensuring optimal conditions during the introduction of cells. To further enhance functionality, anti-inflammatory agents can be integrated into the membrane to minimize immune responses, while growth factors can stimulate cell culture. Post-coating techniques may also be applied to create a protective barrier against immunogenic threats.

Career Highlights

Flanagan's work at Cytotherapeutics, Inc. stands out as a pivotal point in his career. At this firm, he collaborates with other talented professionals in the realm of innovative cellular technologies.

Collaborations

His co-workers include Keith E. Dionne and Orion D. Hegre, who contribute their expertise and insights, complementing Flanagan's vision of advancing biocompatible solutions. Through their collaborative efforts, they aim to push the boundaries of cellular implantation technologies, improving medical outcomes for patients in need of such advanced treatments.

Conclusion

In summary, Thomas R. Flanagan has established himself as a noteworthy inventor in the field of biocompatible technologies, particularly with his patented work on inner-supported cell capsules. His contributions at Cytotherapeutics, Inc. alongside esteemed colleagues underline the potential for innovation in the medical and biological fields. Flanagan's inventions not only exemplify creativity and scientific advancement but also hold promise for future enhancements in cellular therapy.