Thomas P McNicholas

Title: Thomas P McNicholas: Innovator in Photoluminescent Nanostructures

Introduction

Thomas P McNicholas is a prominent inventor based in Cambridge, MA (US). He has made significant contributions to the field of nanotechnology, particularly in the development of photoluminescent nanostructures for sensing applications. With a total of 3 patents, his work has the potential to impact various biomedical and analytical fields.

Latest Patents

One of McNicholas's latest patents is focused on photoluminescent nanostructure-based sensors. This invention describes a composition for sensing an analyte that includes a photoluminescent nanostructure complexed to a sensing polymer. The sensing polymer consists of an organic polymer non-covalently bound to the photoluminescent nanostructure and an analyte-binding protein covalently bound to the organic polymer. This analyte-binding protein is capable of selectively binding the analyte and undergoes a substantial conformational change upon binding.

Another notable patent involves near-infrared fluorescent single-walled carbon nanotubes as tissue-localizable biosensors. This nanosensor for detecting an analyte includes a substrate, a photoluminescent nanostructure, and a polymer that interacts with the photoluminescent nanostructure. The nanosensor is designed for in vivo applications in the biomedical field.

Career Highlights

Thomas P McNicholas is affiliated with the Massachusetts Institute of Technology, where he conducts his research and development work. His innovative approaches to nanotechnology have garnered attention in both academic and industrial circles.

Collaborations

Throughout his career, McNicholas has collaborated with notable colleagues, including Michael S Strano and Nicole M Iverson. These collaborations have further enriched his research and contributed to the advancement of the field.

Conclusion

Thomas P McNicholas is a distinguished inventor whose work in photoluminescent nanostructures is paving the way for new sensing technologies. His contributions are expected to have a lasting impact on various scientific and medical applications.