Company Filing History:
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Years Active: 1999-2000
Title: **The Innovative Journey of Thomas L. Jetton: Pioneering Research in Cancer Genetics**
Introduction
Thomas L. Jetton, an esteemed inventor based in Kingston Springs, TN, has made significant contributions to the field of cancer genetics through his innovative research and patents. With a total of two patents to his name, Jetton has primarily focused on the characterization and therapeutic methods related to BRCA1 and BRCA2 proteins, which are pivotal in understanding familial breast and ovarian cancer.
Latest Patents
Jetton's notable patents include critical advancements in the genetic analysis of familial breast and ovarian cancer. His work on BRCA1 revealed that it is a tumor suppressor gene encoding a 190 kDa protein, which bears sequence homology to the granin family of proteins. His research demonstrated that BRCA1 localizes to secretory vesicles and is secreted, functioning as a tissue-specific growth inhibitor that inhibits the growth and tumorigenesis of breast and ovarian cancer cells. Additionally, Jetton's investigation into BRCA2 further indicated that this gene also encodes a protein with granin characteristics, thus supporting the notion of BRCA2 as a secreted tumor suppressor. His patents also describe therapeutic methods involving BRCA proteins and a method for screening their receptors, broadening the horizons for cancer treatment options.
Career Highlights
Throughout his career, Jetton has been affiliated with reputable institutions such as Vanderbilt University and the University of Washington. His work has not only contributed to the scientific community but also paved the way for new therapeutic applications targeting cancer treatment and diagnosis.
Collaborations
Jetton has had the privilege of collaborating with prominent researchers in his field, including Jeffrey T. Holt and Roy A. Jensen. These collaborations have been instrumental in developing innovative approaches to cancer research, leading to a deeper understanding of vital genetic factors influencing cancer therapies.
Conclusion
In summary, Thomas L. Jetton's groundbreaking research and innovative spirit in the field of cancer genetics exemplify the vital role inventors play in advancing medical science. His patents related to BRCA1 and BRCA2 proteins not only enhance our understanding of cancer mechanisms but also open up new avenues for therapeutic interventions, demonstrating the impact of innovation on health and wellness.