This inventor holds 6 USPTO granted patents. Top assignee: University of California. Active years: 1999-2006.
Company Filing History:
Years Active: 1999-2006
Title: Thomas L Innerarity: Innovator in Atherosclerosis Research
Introduction
Thomas L Innerarity is a prominent inventor based in Lafayette, CA (US). He has made significant contributions to the field of medical research, particularly in understanding and controlling atherosclerosis. With a total of 6 patents to his name, Innerarity's work focuses on innovative methods and tools that have the potential to impact cardiovascular health.
Latest Patents
One of Innerarity's latest patents is titled "Methods and tools for identifying compounds which modulate atherosclerosis by impacting LDL-proteoglycan binding." This invention relates to the study and control of atherosclerosis through the modulation of LDL-proteoglycan binding at Site B (amino acids 3359–3369) of the apo-B100 protein in LDL. The invention encompasses methods for identifying compounds that modulate LDL-proteoglycan binding, as well as methods for identifying compounds that influence atherosclerotic lesion formation. Additionally, it includes methods for modulating the formation of atherosclerotic lesions. The invention also covers mutant apo-B100 proteins and LDL that exhibit reduced proteoglycan binding while maintaining LDL-receptor binding, along with polynucleotides encoding these proteins, and cells and animals that express the mutant apo-B100 proteins.
Career Highlights
Thomas L Innerarity is affiliated with the University of California, where he continues to advance his research in atherosclerosis. His work has garnered attention for its potential to lead to new therapeutic strategies in cardiovascular medicine.
Collaborations
Innerarity collaborates with Erwin H Ludwig, contributing to the innovative research environment at the University of California.
Conclusion
Thomas L Innerarity's contributions to the field of atherosclerosis research highlight his role as a key innovator. His patents and ongoing work promise to enhance our understanding of cardiovascular health and disease management.