Location History:
- Charlottesville, FL (US) (2019)
- Charlottesville, VA (US) (2020)
Company Filing History:
Years Active: 2019-2020
Title: Thomas K Connellan: Innovator in Biofilm Treatment
Introduction
Thomas K Connellan is a notable inventor based in Charlottesville, VA, who has made significant contributions to the field of biofilm treatment. With a total of two patents to his name, Connellan's work focuses on innovative methods to prevent and treat biofilms, which are clusters of microorganisms that can adhere to surfaces and pose challenges in various medical and industrial settings.
Latest Patents
Connellan's latest patents include compositions and methods to prevent and treat biofilms. These patents are based on the discovery of the role of the disaccharide trehalose in microbial biofilm development. The methods disclosed involve administering trehalase, an enzyme that degrades trehalose, in combination with other saccharidases. This approach aims to adequately degrade the biofilm gel matrix at the site of the biofilm. Additionally, the methods include the use of other enzymes such as proteolytic, fibrinolytic, and lipolytic enzymes to break down proteins and lipids present in the biofilm. Antimicrobials are also administered to target specific infectious pathogens underlying the biofilm. Furthermore, Connellan's patents address the degradation of biofilms on medical device surfaces and in industrial settings.
Career Highlights
Connellan's career is marked by his dedication to advancing the understanding and treatment of biofilms. His innovative approaches have the potential to improve patient outcomes in medical settings and enhance the efficiency of industrial processes. His work is recognized for its scientific rigor and practical applications.
Collaborations
Connellan has collaborated with notable colleagues, including Svetlana A Ivanova and Dennis W Davis, to further his research and development efforts in the field of biofilm treatment.
Conclusion
Thomas K Connellan's contributions to the field of biofilm treatment through his innovative patents highlight his role as a leading inventor in this area. His work not only addresses critical challenges in healthcare but also has implications for various industrial applications.