Company Filing History:
Years Active: 2000-2014
Title: Thomas G Back: Innovator in Cardiac Therapy and Oxidative Stress Protection
Introduction
Thomas G Back is a notable inventor based in Calgary, Canada, recognized for his contributions to medical science through innovative patents. With a total of five patents to his name, he has made significant strides in the fields of cardiac therapy and cellular protection against oxidative stress.
Latest Patents
Among his latest patents is the invention of ryanodine receptor inhibitors and methods relating thereto. This invention provides novel ryanodine receptor type 2 (RyR2) inhibitors and methods for their use in treating cardiac conditions. The RyR2 inhibitors assist in normalizing intracellular calcium homeostasis, which is crucial for heart function. In certain embodiments, these inhibitors are store-overload-induced calcium release (SOICR) inhibitors that minimally inhibit or do not inhibit calcium-induced calcium release (CICR), thereby offering beneficial effects in cardiac therapy. Another significant patent is related to glutathione peroxidase mimetics and their uses. This invention involves novel organoselenium and tellurium compounds that act as mimetics for the catalyst selenoenzyme glutathione peroxidase, which protects cells from oxidative stress.
Career Highlights
Throughout his career, Thomas G Back has worked with various companies, including Uti Limited Partnership and Agritope, Inc. His work in these organizations has contributed to the development of innovative solutions in the medical field.
Collaborations
Thomas has collaborated with notable individuals such as Richard Persons Pharis and Suanne K Nakajima, enhancing the impact of his inventions through teamwork and shared expertise.
Conclusion
Thomas G Back's innovative work in developing ryanodine receptor inhibitors and glutathione peroxidase mimetics showcases his commitment to advancing medical science. His contributions have the potential to significantly improve treatment options for cardiac conditions and oxidative stress-related issues.