Company Filing History:
Years Active: 2007
Title: Thomas Fröhlich – Innovator in Mutation Analysis
Introduction
Thomas Fröhlich is an accomplished inventor based in Leipzig, Germany. With a focus on advancements in genetic analysis, Fröhlich has made significant contributions to the field of mass spectrometry. His innovative ideas have led to a patent that enhances the process of detecting genetic mutations.
Latest Patents
Fröhlich holds a patent titled "Mutation analysis by mass spectrometry using photolytically cleavable primers." This invention introduces a novel method for mass-spectrometric analysis, specifically targeting known mutation sites in the genome, such as single nucleotide polymorphisms (SNPs). The inventive technique utilizes primers with photocleavable linkers, which create gaps in DNA strands nearly identical to natural DNA building blocks. This innovation allows for effective hybridization and enzymatic extension while enabling the primers to be cleaved after extension. Consequently, this produces short DNA fragments that are easier to detect using mass spectrometry.
Career Highlights
Fröhlich is affiliated with Bruker Saxonia Analytik GmbH, a company noted for its expertise in analytics and innovative instrumentation. His work contributes to the cutting-edge developments in mass spectrometry, and his efforts in genetic analysis are pivotal in understanding genomic variations.
Collaborations
Throughout his career, Thomas Fröhlich has collaborated with notable colleagues, including Markus Kostrzewa and Thomas Wenzel. Together, they have worked towards advancing the capabilities of analytical techniques, enhancing the potential for groundbreaking discoveries in the realm of genetics.
Conclusion
Thomas Fröhlich exemplifies the spirit of innovation within the realm of genetic analysis and mass spectrometry. His patent not only reflects his dedication to advancing scientific knowledge but also highlights the importance of collaboration in driving innovation forward. The impact of his work will continue to resonate within research institutions and the biotechnology industry.