Thomas Francis Boucher

Title: Innovations by Thomas Francis Boucher

Introduction

Thomas Francis Boucher is an accomplished inventor based in Boston, MA. He has made significant contributions to the field of biotechnology, particularly in the area of neoantigen identification and therapeutic epitope presentation. With a total of two patents to his name, Boucher is recognized for his innovative approaches to cancer treatment.

Latest Patents

Boucher's latest patents include "Reducing junction epitope presentation for neoantigens" and "Neoantigen identification using hotspots." The first patent focuses on designing a cassette sequence that minimizes the likelihood of junction epitopes being presented in patients. This is achieved by considering the presentation of junction epitopes that span between therapeutic epitopes. The second patent outlines a method for identifying neoantigens likely to be presented on tumor cell surfaces. This involves sequencing tumor cells to obtain peptide sequences and using a machine-learned presentation model to generate presentation likelihoods for these neoantigens.

Career Highlights

Boucher is currently employed at Gritstone Bio, Inc., where he continues to advance his research in cancer immunotherapy. His work is pivotal in developing new therapeutic strategies that could improve patient outcomes.

Collaborations

Some of Boucher's notable coworkers include Brendan Bulik-Sullivan and Roman Yelensky. Their collaborative efforts contribute to the innovative research environment at Gritstone Bio, Inc.

Conclusion

Thomas Francis Boucher is a notable inventor whose work in neoantigen research is paving the way for advancements in cancer treatment. His patents reflect a commitment to improving therapeutic strategies and enhancing patient care.