This inventor holds 3 USPTO granted patents and 2 EPO patents. Top assignee: Hoffmann-La Roche Inc.. Active years: 2013-2023.
Location History:
- Pullach, DE (2013 - 2015)
- Penzberg, DE (2023)
Company Filing History:
Years Active: 2013-2023
Title: Thomas Dams: Innovator in Glycoengineering and Chromatography
Introduction
Thomas Dams is a notable inventor based in Pullach, Germany. He has made significant contributions to the fields of glycoengineering and chromatography, holding a total of 3 patents. His work focuses on enhancing the efficacy of antibodies and improving chromatography techniques.
Latest Patents
One of his latest patents is titled "Method for in vitro glycoengineering of antibodies." This patent describes a method for the enzymatic production of an antibody with a modified glycosylation in the Fc-region. The process involves incubating the antibody light chain affinity ligand-bound monoclonal antibody with a glycosylation in the Fc-region using a first enzyme, followed by recovery and further modification with a second enzyme. The final step includes separating the antibody with the modified glycosylation in the Fc-region through cation exchange chromatography.
Another significant patent is "Chromatography equipment characterization." This invention outlines a method for determining whether a re-usable chromatography column packing has reduced separation efficacy during the purification of a polypeptide. The method includes identifying changes in physicochemical parameters, fitting experimental data, and calculating differences to assess the column's performance.
Career Highlights
Throughout his career, Thomas Dams has worked with prominent companies such as Hoffmann-La Roche Inc. and F. Hoffmann-La Roche AG. His experience in these organizations has allowed him to develop and refine his innovative techniques in the field of biochemistry.
Collaborations
Thomas has collaborated with notable professionals in his field, including Anton Belousov and Benjamin Gerwat. These collaborations have contributed to the advancement of his research and the successful development of his patents.
Conclusion
Thomas Dams is a distinguished inventor whose work in glycoengineering and chromatography has led to significant advancements in the field. His innovative methods and collaborations continue to influence the industry positively.