Company Filing History:
1 out of 832,966 Years Active: 2015
Title: Thomas Clarke, IV: Innovator in Molecular Constructs
Introduction
Thomas Clarke, IV is a notable inventor based in Notre Dame, IN (US). He has made significant contributions to the field of molecular biology, particularly in the area of ribosomal translational events. His innovative work has implications for understanding protein synthesis and addressing diseases related to protein accumulation.
Latest Patents
Thomas Clarke, IV holds a patent for "Molecular constructs and uses thereof in ribosomal translational events." This patent describes stalled ribosome:nascent molecule of interest complexes and methods for their use. The invention includes plasmids, particularly DNA plasmids, that comprise a stall segment. These methods facilitate the stable formation of stalled ribosome:nascent molecule complexes, which can be utilized to examine protein synthesis and conformational events. The patent also discusses the creation of desired ribosomal displays and includes cells transformed with these plasmids, encompassing both eukaryotic and prokaryotic cells. Additionally, stall elements that induce ribosomal stalling in both types of ribosomes are disclosed, along with various therapeutic and clinical applications for diseases associated with defects in protein accumulation in vivo. Thomas Clarke, IV has 1 patent to his name.
Career Highlights
Throughout his career, Thomas Clarke, IV has focused on advancing the understanding of molecular constructs and their applications in biological systems. His research has contributed to the development of innovative methods that enhance the study of protein synthesis and its related processes.
Collaborations
Thomas Clarke, IV has collaborated with notable colleagues, including Patricia L Clark and Michael Scott Evans. These partnerships have fostered a collaborative environment that promotes innovation and the advancement of scientific knowledge.
Conclusion
Thomas Clarke, IV is a distinguished inventor whose work in molecular constructs has the potential to impact various fields, particularly in understanding protein synthesis and addressing related diseases. His contributions continue to shape the landscape of molecular biology and innovation.