Thomas Burris

Title: Thomas Burris: Innovator in Nuclear Hormone Receptor Modulation

Introduction

Thomas Burris is a prominent inventor based in Palm Beach Gardens, FL (US). He has made significant contributions to the field of nuclear hormone receptor modulation. His innovative work focuses on developing small molecule modulators that can effectively target specific receptors involved in various biological processes.

Latest Patents

Thomas Burris holds a patent for his invention titled "Modulators of the nuclear hormone receptor ROR." This invention provides small molecule modulators of retinoic acid receptor-related orphan receptors such as RORα, RORβ, or RORγ. The compounds he developed are characterized by a hydroxyl- or alkoxyl-substituted fluoroalkyl group. These compounds can act as effective modulators at concentrations that do not affect LXR receptors or other nuclear receptors. Additionally, his invention includes methods for treating metabolic disorders, immune disorders, cancer, and CNS disorders where modulation of an ROR is medically indicated. He has 1 patent to his name.

Career Highlights

Thomas Burris is associated with The Scripps Research Institute, where he continues to advance his research and innovations. His work has garnered attention for its potential applications in treating various health conditions.

Collaborations

Throughout his career, Thomas has collaborated with notable colleagues, including Theodore M. Kamenecka and Patrick Griffin. These collaborations have contributed to the advancement of research in the field of nuclear hormone receptors.

Conclusion

Thomas Burris is a key figure in the development of modulators for nuclear hormone receptors, with a focus on addressing significant health challenges. His innovative contributions continue to impact the scientific community and hold promise for future medical advancements.