Thomas A. Zangle, based in Salt Lake City, UT, has made notable contributions to the field of immunology through his innovative work focused on T lymphocytes. With one patent to his name, Zangle's research explores methods to identify and isolate specific T cell receptors, which play a critical role in immune responses.

Latest Patents

Zangle’s patent, titled "Selecting and isolating desirable T lymphocytes by change in mass responses," presents a groundbreaking method for identifying T cell receptors responding to specific target cell antigens. The process involves using a substrate with multiple target cells, engaging these cells with CD8+ T cells, and employing label-free optical imaging techniques to track changes in mass. An increase in T cell mass or a decrease in target cell mass signifies that the T cell is activated by the antigens presented on those target cells, enhancing our understanding of immune system dynamics.

Career Highlights

Throughout his career, Thomas A. Zangle has been affiliated with the University of California, where he has collaborated with esteemed colleagues and researchers. His work has significantly advanced the methods used to study T cells, thereby contributing to advancements in immunotherapy and other medical applications.

Collaborations

Zangle has worked alongside prominent researchers such as Michael A. Teitell and Owen N. Witte. Their collective expertise has fostered innovative research directions and has contributed to a deeper understanding of immune functions and therapies.

Conclusion

Thomas A. Zangle exemplifies the spirit of innovation in the scientific community. His patent and research on T lymphocytes reveal promising avenues for understanding and manipulating immune responses, paving the way for future advancements in immunology and therapeutic techniques.

This text is generated by artificial intelligence and may not be accurate.