Location History:
- Chantilly, VA (US) (1997)
- Newton, PA (US) (2003)
- Oak Hill, VA (US) (2013 - 2020)
Company Filing History:
4 out of 16,080 
2 out of 8,684 
1 out of 4 Years Active: 1997-2020
Title: Thomas A. Davis: Innovator in Clinical Decision Models and Allograft Tolerance
Introduction
Thomas A. Davis is a notable inventor based in Oak Hill, VA (US). He holds a total of 5 patents that reflect his contributions to the fields of clinical decision-making and immunology. His innovative approaches have the potential to significantly impact patient care and treatment outcomes.
Latest Patents
One of his latest patents is a Clinical Decision Model. This invention provides a method for determining a patient-specific probability of disease. The method collects clinical parameters from a plurality of patients to create a training database. A fully unsupervised Bayesian Belief Network model is created using data from the training database, and this model is validated. Clinical parameters are collected from an individual patient and input into the model via a graphical user interface. The output is a patient-specific probability of the healing rate of an acute traumatic wound, which is sent to the graphical user interface for use by clinicians in pre-operative planning. The model is continuously updated with clinical parameters from individual patients.
Another significant patent is related to Allograft Tolerance Induction. This method induces chimerism and allograft tolerance by co-infusion of stem/progenitor-like cells and donor cells, which can include bone marrow cells. The method involves conditioning that depletes CD4+ and CD8+ T-cells and administers low doses of anti-neoplastic drugs. Notably, this inventive method induces allograft tolerance without systemically suppressing the immune system.
Career Highlights
Throughout his career, Thomas A. Davis has worked with prominent organizations, including the USA as represented by the Secretary of the Navy and the US Government as represented by the Secretary of the Army. His work in these institutions has allowed him to contribute to significant advancements in medical technology and patient care.
Collaborations
Thomas has collaborated with notable professionals in his field, including Eric Elster and Alexander Stojadinovic. These collaborations have further enriched his research and development efforts.
Conclusion
Thomas A. Davis is a distinguished inventor whose work in clinical decision models and allograft tolerance has the potential to transform medical practices. His innovative patents and collaborations highlight his commitment to advancing healthcare solutions.