Company Filing History:
2 out of 155 
1 out of 1 Years Active: 2018-2023
Title: Innovations in Cancer Treatment by Inventor Theresa Bunse
Introduction
Theresa Bunse is a prominent inventor based in Heidelberg, Germany. She has made significant contributions to the field of cancer therapeutics and diagnostics. Her innovative work focuses on developing novel immunogenic peptide sequences that can be utilized as vaccines for treating various cancer diseases, particularly glioma.
Latest Patents
Theresa Bunse holds 2 patents that showcase her groundbreaking research. One of her latest patents involves histone anti-cancer vaccines. This invention pertains to novel immunogenic peptide sequences designed for the treatment of cancer diseases, including brain cancers such as glioma. The cancer vaccines are based on the K27M mutated variant of human Histone 3. The invention also includes fusion proteins, nucleic acids encoding the vaccines, and vectors and host cells that comprise these sequences. Additionally, it addresses T cells and T cell receptors that bind to the cancer vaccines, eliciting a HLA-restricted immune response, which is crucial for treating glioma.
Another significant patent concerns methods and means for treating or diagnosing IDH1 R132H mutant-positive cancers. This invention relates to a peptide that comprises at least 8 amino acids in length from the human Isocitrate dehydrogenase Type 1 (IDH1). The peptide has an amino acid exchange from R to H at position 132, which is essential for preventing and treating cancer. The invention also includes a method for diagnosing cancer characterized by the expression of a mutant IDH1, along with a kit and device for carrying out the diagnostic method.
Career Highlights
Throughout her career, Theresa Bunse has worked with esteemed institutions such as the German Cancer Research Center (Deutsches Krebsforschungszentrum) and Ruprecht-Karls-University Heidelberg. Her work has significantly advanced the understanding and treatment of cancer, particularly through her innovative vaccine development.
Collaborations
Theresa has collaborated with notable colleagues, including Michael Platten and Wolfgang Wick. Their combined expertise has contributed to the success of her research and the development of her patents.
Conclusion
Theresa Bunse's innovative contributions to cancer treatment through her patents and research highlight her role as a leading inventor in the field. Her work continues to pave the way for advancements in cancer therapeutics and diagnostics.