Company Filing History:
14 out of 21,595 
1 out of 92 
Years Active: 1977-1996
Title: **Inventor Theodore W. Esders: A Pioneer in DNA Amplification Technologies**
Introduction
Theodore W. Esders, based in Webster, NY, is a notable inventor recognized for his significant contributions to the field of molecular biology. With a remarkable portfolio of 15 patents, Esders has focused primarily on innovations related to DNA amplification technologies. His work has facilitated advancements in diagnostic test kits, particularly in the polymerase chain reaction (PCR) methods crucial for various applications in genetics and medical research.
Latest Patents
Among Theodore W. Esders' latest patents is the invention of thermostable polymerase specific antibody-containing DNA amplification. This groundbreaking innovation utilizes antibodies that are specific to a thermostable DNA polymerase, aiming to reduce or eliminate the formation of non-specific products during PCR processes. The antibodies, along with other temperature-sensitive inhibitors, effectively inhibit DNA polymerase enzymatic activity at a specific temperature T₁, generally below 85°C. Notably, these inhibitors become irreversibly inactivated at a higher temperature T₂, which is above 40°C and greater than T₁. Esders’ patents can be incorporated either individually or as admixtures with DNA polymerase in commercial diagnostic test kits for PCR applications.
Career Highlights
Theodore W. Esders has worked with notable companies such as Eastman Kodak Company and Johnson & Johnson Clinical Diagnostics, Inc. His experience in these renowned institutions has helped him hone his skills in biotechnology and innovation. His inventive efforts have led to new methodologies gaining traction in research and clinical diagnostics.
Collaborations
Throughout his career, Esders has collaborated with esteemed colleagues, including Charles T. Goodhue and Christine A. Michrina. This collaboration has contributed to the advancement of novel techniques in DNA amplification and molecular diagnostics, showcasing the innovative spirit shared among scientists in their pursuit of discovery.
Conclusion
In summary, Theodore W. Esders exemplifies the impact that dedicated inventors can have on science and technology. With his remarkable contributions to DNA amplification technologies, he continues to influence the fields of molecular biology and diagnostics. His innovative approaches not only enhance the accuracy of testing methods but also ease the pathway for future advancements in these essential areas of research.