Theodore S Wang

Title: The Innovations of Theodore S. Wang

Introduction

Theodore S. Wang is a notable inventor based in Lexington, MA (US). He has made significant contributions to the field of pharmacology, particularly in the development of neuromuscular blocking agents. His work has implications for medical practices involving anesthesia and muscle relaxation.

Latest Patents

Wang holds a patent for neuromuscular blocking agents and antagonists. The patent discloses that 2-(4'-pyridyl)-1,3-dioxolane methiodide and 2-(1'-methyl-4'-piperidyl)-1,3-dioxolane hydroiodide can function as neuromuscular blocking agents or antagonists, depending on the dosage administered. At doses ranging from 10^-6 to 10^-4 gm./kg. of body weight, these compounds can reverse the effects of neuromuscular blocking agents like d-tubocurarine and succinylcholine. They also produce post-drug repetitive activity (PDR) and block post-tetanic potentiation (PTP), without having a direct muscle effect. At higher doses, from 10^-3 to 10^-2 gm./kg. of body weight, they act as neuromuscular blocking agents.

Career Highlights

Wang is associated with Bristol-Myers Company, where he has been able to apply his innovative ideas in a collaborative environment. His work has been instrumental in advancing the understanding and application of neuromuscular agents in clinical settings.

Collaborations

Wang has worked alongside Julius A. Vida, contributing to the development of new pharmacological solutions. Their collaboration has led to advancements in the field, enhancing the efficacy and safety of neuromuscular blocking agents.

Conclusion

Theodore S. Wang's contributions to the field of pharmacology through his patent on neuromuscular blocking agents highlight his innovative spirit and dedication to improving medical practices. His work continues to influence the development of safer and more effective anesthetic techniques.