Company Filing History:
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1 out of 3,540 
Years Active: 1998
Title: Thea Kalebic: Innovator in HIV Research
Introduction
Thea Kalebic is a notable inventor based in Bethesda, MD (US), recognized for her contributions to the field of HIV research. She has developed innovative solutions aimed at suppressing HIV expression, showcasing her commitment to advancing medical science.
Latest Patents
Kalebic holds a patent for the invention titled "Suppression of HIV expression by organic thiophosphate." This patent addresses chronic HIV infection by administering an organic thiophosphate, either alone or in combination with other anti-HIV or anti-AIDS drugs. The preferred compound, WR 151327, exhibits antioxidant and free radical scavenging activities. It effectively suppresses the induction of HIV expression in chronically infected cells, mediated by cytokines such as TNF.alpha. and GM-CSF. The patent also discloses pharmaceutical compositions that combine at least one organic thiophosphate with one or more anti-HIV or anti-AIDS drugs.
Career Highlights
Throughout her career, Thea Kalebic has worked with prominent organizations, including U.S. Bioscience, Inc. and the National Institutes of Health, specifically within the National Cancer Institute. Her work in these institutions has significantly contributed to the understanding and treatment of HIV.
Collaborations
Kalebic has collaborated with notable professionals in her field, including Philip S. Schein, enhancing the impact of her research through shared expertise and knowledge.
Conclusion
Thea Kalebic's innovative work in HIV research and her patent for suppressing HIV expression highlight her significant contributions to medical science. Her dedication to finding effective treatments for chronic HIV infection continues to inspire advancements in the field.