This inventor holds 2 USPTO granted patents. Top assignee: Columbia University. Active years: 2017-2019.
Company Filing History:
Years Active: 2017-2019
Title: Innovations of Thaned Kangsamaksin
Introduction
Thaned Kangsamaksin is a notable inventor based in Lampang, Thailand. He has made significant contributions to the field of biotechnology, particularly in the development of fusion proteins related to the human Notch1 receptor. With a total of 2 patents, his work has implications for treating various medical conditions.
Latest Patents
Kangsamaksin's latest patents focus on Human Notch1 decoys. These patents describe Notch1 fusion proteins that consist of consecutive amino acids, starting from the N-terminus of the fusion protein. The sequence is identical to that of the extracellular domain of a human Notch1 receptor protein and includes an Fc portion of an antibody. The amino acid sequence of the extracellular domain (ECD) begins with the amino acid at the N-terminus of EGF-like repeat 10 and extends through the C-terminal amino acid of EGF-like repeat 23. The N-terminal portion of the ECD may extend up to the C-terminal amino acid of EGF-like repeat 24 or 36. Additionally, the patents provide methods for treating age-related macular degeneration (AMD), diabetic retinopathy, and cancer using these fusion proteins.
Career Highlights
Thaned Kangsamaksin is affiliated with Columbia University, where he continues to advance his research in biotechnology. His innovative work has garnered attention in the scientific community, contributing to the understanding of Notch signaling pathways.
Collaborations
Some of his notable coworkers include Carrie Shawber and Jan K Kitajewski. Their collaborative efforts have further enhanced the research and development of therapeutic applications related to Kangsamaksin's inventions.
Conclusion
Thaned Kangsamaksin's contributions to biotechnology through his patents on Human Notch1 decoys highlight the potential for innovative treatments in medicine. His work exemplifies the intersection of research and practical applications in healthcare.