Company Filing History:

6 out of 4,943

Hoffmann-la Roche Inc.

Years Active: 1990-2010

Loading Chart...

14 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 7670814 - Microbial production of vitamin C (2010-03-02),

2. 7544494 - Vitamin C from sorbosone (2009-06-09),

3. 7341854 - Microbial production of vitamin C (2008-03-11),

4. 7135315 - Aldehyde dehydrogenase gene (2006-11-14),

5. 6846660 - Method of making an aldehyde dehydrogenase with gluconobacter (2005-01-25),

6. 6242233 - Aldehyde dehydrogenase (2001-06-05),

7. 5776742 - Aldehyde dehydrogenase enzyme (1998-07-07),

8. 5747301 - D-sorbitol dehydrogenase (1998-05-05),

9. 5541108 - Gluconobacter oxydans strains (1996-07-30),

10. 5312741 - Process for producing 2-keto-L-gulonic acid (1994-05-17),

11. 5250428 - L-gulono-gamma-lactone-dehydrogenase for producing vitamin C (1993-10-05),

12. 4960695 - Fermentation process to produce 2-keto-L-gluonic acid (1990-10-02),

13. 4916069 - Enzyme and process for producing the same (1990-04-10),

14. 4902617 - Enzyme and process for producing the same (1990-02-20),

Title: The Pioneering Work of Inventor Teruhide Sugisawa

Introduction

Teruhide Sugisawa is a notable inventor based in Yokohama, Japan, renowned for his contributions to the field of biotechnology. With an impressive portfolio of 14 patents, he has made significant strides in the microbial production of valuable substances, including the essential vitamin C.

Latest Patents

Sugisawa's latest innovations include a groundbreaking process for the production of vitamin C from substrates like L-sorbosone. This invention leverages a microorganism belonging to the genus that utilizes aldehyde dehydrogenase, specifically isolated from DSM 4025 (FERM BP-3812). The enzyme has several intriguing physicochemical properties, including a molecular weight of approximately 150,000 ± 6,000 Da or 230,000 ± 9,000 Da, along with substrate specificity that is active on aldehyde compounds. Additionally, the process operates optimally between pH levels 6.4 and 8.2 while producing vitamin C. Notably, certain metal ions and agents inhibit this process, providing a comprehensive understanding of the production mechanism.

Career Highlights

Throughout his career, Sugisawa has been associated with esteemed companies, including Hoffmann-La Roche Inc. and DSM IP Assets B.V., where he has contributed to various innovative projects. His dedication and expertise in the field have allowed him to develop multiple patents that enhance the production and applications of biochemicals.

Collaborations

Sugisawa has also collaborated with other prominent figures in the industry, including Tatsuo Hoshino and Taro Miyazaki. These partnerships have fostered a spirit of innovation and creativity, resulting in advancements that push the boundaries of biotechnology.

Conclusion

Teruhide Sugisawa's contributions to the field of biotechnology and his array of patents highlight his role as a significant figure in the evolution of microbial production processes. His innovative approaches and collaborations continue to pave the way for future advancements in the production of essential vitamins and other biochemicals.

This text is generated by artificial intelligence and may not be accurate.

Please report any incorrect information to support@idiyas.com

Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.