Durham, NC, United States of America

Terrence P Kenakin


Average Co-Inventor Count = 2.6

ph-index = 3

Forward Citations = 15(Granted Patents)


Company Filing History:


Years Active: 1991-1993

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6 patents (USPTO):

Title: The Innovative Journey of Terrence P. Kenakin

Introduction: Terrence P. Kenakin is an accomplished inventor based in Durham, North Carolina, known for his significant contributions to the field of pharmaceutical inventions. With a remarkable portfolio of six patents, Kenakin has focused his research on developing innovative compounds that target various health conditions, particularly in the cardiovascular domain.

Latest Patents: Among his latest inventions are novel dihydropyridine vasodilators. These compounds, defined by a specific formula, present potential applications as antihypertensives or myocardial relaxants. The intricate structures involve substituents like alkyl, cycloalkyl, and aryl groups, together with oxygen-containing linking groups. Additionally, Kenakin has developed substituted methoxyphenyl-4,5 dihydro-3(2H)-pridazinones. This innovative class of pyridazinones aims to treat congestive heart failure, incorporating a new pharmaceutical composition, novel intermediates, and effective treatment methodologies.

Career Highlights: Kenakin's career is marked by his significant role at Glaxo Inc., where he has been pivotal in advancing pharmaceutical research. His inventiveness is not only evident in his patented compounds but also in his ability to bridge theory and practice, making a real-world impact on treatments for heart-related conditions.

Collaborations: Throughout his career, Kenakin has worked alongside notable colleagues such as Thomas N. Wheeler and Joel E. Shaffer. These collaborations have fostered a rich environment for innovation and have contributed to the successful development of his patented compounds.

Conclusion: Terrence P. Kenakin stands as a pivotal figure in the field of pharmaceuticals, with his six patents underscoring a commitment to innovation. His work on dihydropyridine vasodilators and pyridazinones reflects a deep understanding of medicinal chemistry, aiming to improve treatment for cardiovascular diseases and enhance patient outcomes.

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