Holden, MA, United States of America

Terence Flotte

USPTO Granted Patents = 14 

 

 

Average Co-Inventor Count = 2.9

ph-index = 8

Forward Citations = 256(Granted Patents)


Location History:

  • Holden, MA (US) (2014 - 2024)
  • Worcester, MA (US) (2023 - 2024)

Company Filing History:


Years Active: 2014-2024

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14 patents (USPTO):Explore Patents

Title: The Innovations of Terence Flotte: Pioneering Genetic Therapies

Introduction: Terence Flotte, an accomplished inventor based in Holden, MA, has made significant contributions to the field of genetic therapies. With a remarkable portfolio of 14 patents, Flotte's work focuses on advanced biotechnological methods aimed at treating genetic diseases, particularly through the use of recombinant adeno-associated viruses (rAAV).

Latest Patents: Among his latest innovations, Terence Flotte has developed patents related to RAAV-based compositions and methods. This invention involves isolated nucleic acids and rAAV-based compositions and kits that are designed for the treatment of genetic disorders, including alpha-1 antitrypsin deficiency. Another notable patent covers a campaign-ready series of recombinant adeno-associated virus (rAAV) complementing plasmids. This work outlines methods for producing rAAV particles using a system that requires only two vectors, facilitating the creation of multiple single-gene viral vectors in a small-scale campaign mode.

Career Highlights: As a distinguished member of the University of Massachusetts, Terence Flotte has played a vital role in advancing the research and development of genetic therapies. His tenure at this prestigious institution has allowed him to explore the intersections of biotechnology and medicine, leading to groundbreaking advancements that hold promise for the future of treatment options for genetic diseases.

Collaborations: Terence Flotte's innovative journey is amplified through collaborations with fellow researchers, including Guangping Gao and Jun Xie. Their collective expertise enhances the potential for transformative discoveries in the field of gene therapy, illustrating the power of teamwork in scientific research.

Conclusion: Terence Flotte stands out as a leading inventor whose advancements in genetic therapies through rAAV technology mark an important stride in the pursuit of effective treatments for genetic conditions. With his continued dedication to innovation and research at the University of Massachusetts, the impact of his work is sure to resonate throughout the medical community and beyond.

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