Te-Yen Chien

Title: Te-Yen Chien: Innovator in Transdermal Delivery Systems

Introduction

Te-Yen Chien is a notable inventor based in Branchburg, NJ (US), recognized for his contributions to the field of transdermal drug delivery systems. With a total of eight patents to his name, Chien has made significant advancements in the way pharmaceuticals are administered through the skin.

Latest Patents

Among his latest innovations is a patent for a transdermal controlled delivery system of pharmaceuticals at variable dosage. This system features transdermal polymer dosage units that include a backing layer and a reservoir layer. The reservoir layer can consist of multiple regions that contact the skin, potentially containing different pharmaceuticals, allowing for a variable rate of transdermal absorption. The design includes microreservoirs or macroreservoirs, which are bounded by a backing layer and a non-porous permeability-regulating polymer membrane that interacts with the skin during administration.

Another significant patent is for a transdermal contraceptive delivery system (TCDS) aimed at fertility control in women. This system comprises a backing layer and a solid absorption adhesive polymer matrix that disperses minimum effective daily doses of estrogen and progestin for transdermal absorption. The preferred components include natural estrogen, 17-beta-estradiol, and synthetic progestin, levonorgestrel, along with skin permeation enhancing agents blended in specific ratios.

Career Highlights

Te-Yen Chien is affiliated with Rutgers, the State University of New Jersey, where he continues to innovate in the field of pharmaceutical delivery systems. His work has garnered attention for its potential to improve the efficacy and convenience of drug administration.

Collaborations

Chien has collaborated with notable colleagues, including Yie W Chien and Yih-Chain Huang, contributing to the advancement of transdermal technologies.

Conclusion

Te-Yen Chien's innovative work in transdermal delivery systems showcases his commitment to improving pharmaceutical administration methods. His patents reflect a deep understanding of drug delivery mechanisms and a dedication to enhancing patient care.