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Years Active: 2005-2011
Title: Innovations in Cardiac Treatment by Inventor Tatsuo Katori
Introduction
Tatsuo Katori is a notable inventor based in Baltimore, MD (US), recognized for his contributions to the field of cardiac treatment. He holds 2 patents that focus on innovative approaches to managing heart failure. His work has significant implications for improving myocardial contractility and patient outcomes.
Latest Patents
Katori's latest patents include groundbreaking research on nitroxyl progenitors in the treatment of heart failure. One of his key inventions involves the administration of an HNO/NO donating compound, such as Angeli's salt, which has been shown to increase myocardial contractility while simultaneously lowering left ventricular preload in subjects experiencing heart failure. Furthermore, he discovered that the HNO/NO donating compound isopropylamine (IPA)/NO exhibited positive inotropic effects that surpassed those of Angeli's salt. Notably, Katori's research indicates that the administration of an HNO/NO donor in combination with a positive inotropic agent does not impair the positive effects of the agent. Additionally, his findings reveal that HNO/NO exerts its positive inotropic effect independently of the adrenergic system, enhancing contractility even in patients receiving beta-antagonist therapy.
Career Highlights
Throughout his career, Tatsuo Katori has worked with prestigious organizations, including the National Institutes of Health, a component of the US Department of Health & Human Services, and the University of California. His work in these institutions has allowed him to advance his research and contribute to significant medical innovations.
Collaborations
Katori has collaborated with esteemed colleagues, including David A. Wink and Martin Feelisch, who have contributed to his research endeavors and innovations in cardiac treatment.
Conclusion
Tatsuo Katori's innovative work in the treatment of heart failure showcases his dedication to improving patient care through scientific research and invention. His patents reflect a commitment to advancing medical knowledge and therapeutic options in cardiology.