This inventor holds 8 USPTO granted patents and 1 EPO patent. Top assignees: Central Iowa Health System, Human Gene Therapy Research Institute, Iowa Health System. Active years: 2003-2016.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Ames, IA (US) (2005)
- West Des Moines, IA (US) (2003 - 2016)
Company Filing History:
4 out of 4 
2 out of 11 
1 out of 2 Years Active: 2003-2016
Title: Tatiana Seregina: Pioneering Antitumor Vaccination
Introduction
Tatiana Seregina, an accomplished inventor based in West Des Moines, IA, has made significant contributions to the field of cancer research through her innovative work. With a total of 8 patents, she has focused on developing advanced methods for targeting and killing tumor cells, showcasing her commitment to improving patient outcomes in oncology.
Latest Patents
One of her latest patents, titled "Antitumor vaccination using allogeneic tumor cells expressing alpha (1,3)-galactosyltransferase," relates to methods and compositions designed to selectively target and kill tumor cells. Through ex vivo gene therapy protocols, tumor cells are engineered to express an alpha (1,3)-galactosyl epitope. These cells are subsequently irradiated or otherwise killed and then administered to a patient. The alpha-galactosyl epitope enhances the uptake of the opsonized tumor cells by antigen-presenting cells, resulting in improved tumor-specific antigen presentation. Consequently, the animal's immune system is stimulated to generate tumor-specific cytotoxic cells and antibodies that effectively attack and destroy tumor cells within the body.
Career Highlights
Tatiana Seregina has worked with notable organizations such as Central Iowa Health System and the Human Gene Therapy Research Institute. Her work in these institutions has allowed her to further her research and application of innovative techniques in gene therapy and immunology.
Collaborations
Throughout her career, Tatiana has collaborated with esteemed colleagues including Charles J. Link and Gabriela Rossi. These collaborations have fostered an environment of innovation and shared knowledge, contributing to the advancements in the field of cancer treatment.
Conclusion
Tatiana Seregina's dedication to her work and her innovative patents position her as a key player in the realm of cancer research. Her groundbreaking methodologies not only enhance the targeting of tumor cells but also hold promise for elevating the effectiveness of cancer therapies, marking her as a pivotal inventor in the ongoing battle against cancer.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile