Company Filing History:
Years Active: 2015-2023
Title: Tara Sigdel: Innovator in Organ Transplant Biomarkers
Introduction
Tara Sigdel is a prominent inventor based in Palo Alto, CA (US). She has made significant contributions to the field of organ transplantation through her innovative research and patented inventions. With a total of 3 patents, her work focuses on improving the understanding and management of organ transplant rejection.
Latest Patents
One of Tara Sigdel's latest patents involves the development of protein and gene biomarkers for the rejection of organ transplants. This invention includes methods for determining the transplant category of a subject who has undergone a transplant. By uncovering common mechanisms of rejection injury across different tissue transplants, her work provides insights into rational drug design. The invention examines various sources of tissues from the patient to understand acute rejection mechanisms, utilizing both minimally invasive (blood) and non-invasive (urine for kidney allografts) monitoring techniques. The discovery of different categories of biomarkers, such as genes, proteins, peptides, and antibodies, plays a crucial role in determining the subject's transplant category, including acute allograft rejection, stable allograft, BK viremia, and chronic allograft injury. Additionally, the invention encompasses compositions, systems, kits, and computer program products that facilitate the application of these methods.
Career Highlights
Tara Sigdel is affiliated with Leland Stanford Junior University, where she continues her research and innovation in the field of organ transplantation. Her work has garnered attention for its potential to enhance patient outcomes and improve transplant management.
Collaborations
Tara collaborates with esteemed colleagues, including Minnie M Sarwal and Amit Kaushal, to further advance the research in organ transplant biomarkers.
Conclusion
Tara Sigdel's contributions to the field of organ transplantation through her innovative patents and research are paving the way for improved patient care and understanding of transplant rejection mechanisms. Her work exemplifies the impact of scientific innovation on healthcare.